Cardiovascular safety of anti-diabetic drugs

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Cardiovascular safety of anti-diabetic drugs.

Cardiovascular disease is the leading cause of morbidity and mortality among patients with diabetes, underscoring the importance of choosing anti-diabetic drugs that do not increase cardiovascular risk but might reduce the risk of cardiovascular events. Most type 2 diabetic patients die from cardiovascular causes despite the beneficial effects of blood pressure (BP) and lipid-lowering medicatio...

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Diabetes is a well-known risk factor of cardiovascular morbidity and mortality, and the beneficial effect of improved glycemic control on cardiovascular complications has been well established. However, the rosiglitazone experience aroused awareness of potential cardiovascular risk associated with diabetes drugs and prompted the U.S. Food and Drug Administration to issue new guidelines about ca...

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Medicinal Chemistry of Novel Anti-Diabetic Drugs

Diabetes mellitus is a common metabolic disorder affecting millions of people worldwide. The prevalence of this chronic, endocrine condition continues to grow, from a world-wide prevalence of 221 million in 2010 to a projected 300 million in 2030 [1, 2]. The majority (~90%) of patients suffering from diabetes mellitus have type 2 while about 10% have type 1. Type 1 diabetes is caused by immunol...

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Cardiovascular Safety of Oral Antidiabetic Drugs

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ژورنال

عنوان ژورنال: European Heart Journal - Cardiovascular Pharmacotherapy

سال: 2015

ISSN: 2055-6837,2055-6845

DOI: 10.1093/ehjcvp/pvv035